SRF and muscular dystrophy: The possibility of considering muscular dystrophy a model of accelerated sarcopenia is supported by the observation that the two conditions exhibit marked defects of the autophagy-lysosome system, likely as a consequence of dysfunctional Akt/mTOR/p70S6K pathway and disruption of serum response factor (SRF)-dependent signaling (Sakuma et al., 2014).