GLUL and major depressive disorder: The expression of GS mRNA was reported to be down-regulated in the prefrontal cortex, the premotor cortex, and the amygdala of depressed suicide victims but not in suicide completers without depression (Choudary et al., 2005; Sequeira et al., 2009), whereas GS protein was found to be reduced in the anterior cingulate cortex and the orbitofrontal cortex (Choudary et al., 2005; Beasley et al., 2006; Miguel-Hidalgo et al., 2010; Rajkowska and Stockmeier, 2013).