Prkar1a+/− mice develop tumours consistent with Carney Complex syndrome, which is characterised by increased occurrence of different tumour types including myxomas, schwannomas, and endocrine tumours, which include somatotrophinomas, adrenal cortical tumours, sertoli cell tumours, ovarian cysts and thyroid follicular adenomas (Yin et al., 2008). The gene discussed is PRKAR1A; the disease is neoplasm.