Since the expression pattern of CCL8 was identified in the melanoma cell lines and non-tumoral cells (fibroblasts, melanocyte, keratinocyte) as well as human metastatic and non-metastatic melanoma samples in our metastatic animal model, we raised the question whether there was any correlation between chemokine expression and metastasis formation of human primary melanomas. The gene discussed is CCL8; the disease is melanoma.