We discovered that TRAF6 expression in gliomas was higher than that in the control (P < 0.05 ∼ 0.001) and that its expression was significantly increased with the elevation of glioma grades and was the highest in glioblastoma (P < 0.01 ∼ 0.001; Figure 3A and 3B). This evidence concerns the gene TRAF6 and central nervous system cancer.