Although facilitated lactic acid accumulation by lactic acid transporter MCTs (Monocarboxylate Transporters) was reported in some cancers [35, 36], the expression of lactic acid import transporter MCT1 was low, and the lactic acid export transporter MCT4 was high in HNF1β-high cells (Fig. S1). This evidence concerns the gene SLC16A3 and cancer.