Control-HMLER cells mixed with PBS but not Matrigel formed tumors in 5/15 (33%) mice, and over-CTGF-HMLER cells mixed with PBS elicited tumor formation in 15/15 (100%) injected mice (p = 0.012, Fisher Exact Test), with 25 days earlier on average tumor formation than the control cell-injected mice (Figure 6B). The gene discussed is CCN2; the disease is neoplasm.