Recently, the ablation or inhibition of EIF5A2 was also reported to enhance the chemosensitivity of HCC (hepatocellular carcinoma) cells to 5-fluorouracil (5-FU)/doxorubicin and breast cancer cells and bladder cancer cells to doxorubicin [6–9]. This evidence concerns the gene EIF5A2 and hepatocellular carcinoma.