CXCR4 and neoplasm: In these types of cancers, miR-494 functions its tumor suppressive effects, and inhibites cell proliferation, cell migration, and cell invasion and promoting apoptosis by regulating different oncogenes in different cancer cells, such as VEGF [29], CXCR4 [17], CLPTM1L [16], HOXA10 [30], and c-MYC [27].