NEK1 and neoplasm: The two deleted regions including 4q (4q32.5-q35.1 in tumor sample from Patient 14 and 4q35.2-q28.1 in tumor sample from Patient 8) contained several genes, including NEK1. This gene encodes a protein involved in cilium control and is essential for response to DNA damage, cell cycle progression, and correct transmission of chromosomes to daughter cells.