PTEN and colorectal cancer: In the present study, we have investigated the expression of multiple glucose transporters, glutamine transporters, catalytic enzymes involved in glycolysis and glutaminolysis pathway in NDRG2-overexpressing and knockdown colorectal cancer cells (Supplementary Figure S9), and we have also detected PTEN/Akt signaling pathway in NDRG2-overexpressing colorectal cancer cells (Supplementary Figure S10).