In grade III astrocytomas, there was a moderate correlation between the relative expression levels of Bmi-1 and CDKN2B (r = -0.5824, p<0.05) (Fig 4A), Bmi-1 and CCND1 (r = 0.6099, p<0.05) (Fig 4B), and CDKN2B and CDKN2A (r = 0.5585, p<0.05) (Fig 4C), and there was a strong correlation between the relative expression levels of CDKN2B and CCND1 (r = -0.7967, p<0.01) (Fig 4D) (Table 3). Here, BMI1 is linked to astrocytoma (excluding glioblastoma).