HMGB1 and type 2 diabetes mellitus: Among NGT-NW, NGT-OB, T2DM-NW and T2DM-OB subgroups, the plasma HMGB1 levels in NGT-OB were higher than those in NGT-NW (4.95 ± 0.76 vs 4.44 ± 0.25, P< 0.01), while the plasma HMGB1 concentrations in T2DM-OB were higher than those in T2DM-NW (9.11 ± 0.75 vs 7.43 ± 0.81, P< 0.001).