Consistent with previous findings [10], other BC cell lines showed barely detectable or no BCAR4. Features of BC cell lines with high/moderate BCAR4 mRNA included (i) a luminal subtype, (ii) mutation of CDH1/E-cadherin and (iii) an origin from endocrine-resistant tumors (Fig 1B, lower panel). The gene discussed is BCAR4; the disease is breast cancer.