AKT1 and cancer: AKT SNPs are reported to be associated with susceptibility to and/or the prognosis of various cancer types including nasopharyngeal carcinoma [12], oral squamous cell carcinoma [13, 30], non-small cell lung cancer [14, 15], pancreatic ductal adenocarcinoma [31], and GC [32] via effects on protein expression and transcriptional activity.