AKT, alternatively known as AKT1, has five widely studied polymorphisms (rs3803300, rs1130214, rs2494732, rs2498804, and rs1130233); the first four have been linked to the risk or prognosis of nasopharyngeal carcinoma, oral squamous cell carcinoma, and non-small cell lung cancer. The gene discussed is AKT1; the disease is non-small cell lung carcinoma.