APOE and dementia: Adjustment for age and sex, or for age, sex, and ApoE ε4, nonsignificantly decreased the hazard ratio for the association between tremor and dementia (HR 0.50, 95% CI 0.21 to 1.20, P = 0.12; or HR 0.46, 95% CI 0.17 to 1.23, P = 0.12).