Women had a longer duration of documented HIV infection (median, IQR: 143, 55–210 versus 52, 24–411 months; P = 0.0001), lower CD4 counts at Nadir (median, IQR: 205 cells/mmc, 120–288 versus 273 cells/mmc, 163–397; P = 0.003), and a longer duration of HAART (median, IQR: 70, 33–152 versus 44, 22–130.5 months; P = 0.05) compared with men. This evidence concerns the gene CD4 and HIV infectious disease.