In a previous study that utilized immunohistochemistry to characterize the metabolic phenotype of 740 breast cancers, a greater association of Warburg metabolism was observed in breast cancers that lack expression of hormone receptors (estrogen receptor (ER−), progesterone receptor (PR−), and human epidermal growth factor 2 (HER2−)) [41]. Here, NR4A1 is linked to breast carcinoma.