These cells displayed augmented expression of HIF-1α and HIF-1α-inducible nonglycocytic targets, along with minor increases in the expression of glucose transporters SLC2A1 and SLC2A3. This subpopulation exhibited a gene expression profile most similar to the tumor of origin, which may be due to overrepresentation of these cells within the tumor [23]. Here, SLC2A3 is linked to neoplasm.