The median levels of HMGB1 and IL-10 in DLBCL patients plasma were 17.88 ng/ml and 9.49 pg/ml, respectively, and were higher than previously published normal levels of HMGB1 <10 ng/ml [32] and IL-10 <3 pg/ml [33]. The gene discussed is IL10; the disease is diffuse large B-cell lymphoma.