TNF and Sepsis: In the case of sepsis a significant increase of IL-6 (P = 0.0020), IL-8 (P = 0.0020), sIL-2R (P = 0.0156), and TNF-α (P = 0.0078) was observed in all pediatric patients (n = 8) for which an analysis of the cytokine levels was performed on the day of the occurrence of sepsis.