Sanger sequencing and DNA quantitative PCR of SLC22A16 to detect a CNA loss were performed in an additional 43 cases of DLBCL (patient characteristics shown in Supplementary Figure 5B) and revealed two additional mutations, L325R and H49Y, both of which were in cases that failed to achieve EFS24. The gene discussed is SLC22A16; the disease is diffuse large B-cell lymphoma.