CXCL8 and nasopharyngeal carcinoma: We previously used microarrays to compare the differences of both miRNA and mRNA expression profiles in the NPC cell lines with different radiosensitivity, and found that miR-23a was downregulated, but IL-8 was upregulated in the radioresistant NPC cells, and confirmed that IL-8 is the direct target gene of miR-23a in NPC cells [18].