MMP1 and neoplasm: Similarly, CXCL5, CXCL13, CCL1, CCL7 and CCL26 in WF collected from patients with T1–2 tumor tend to be higher than those with Tis, and the profiles of CXCL13, CCL27, MMP-1 and MMP-7 in WF from N1–3 patients tend to be higher than those with N0 (Table 3).