In our study, the concentrations of IL-23, IL-25, IFNγ, CD40L, TNFα, CXCL5, CXCL13, CCL1, CCL7, CCL26, CCL27, MMP-1 and MMP-7 in WF were in parallel with the TNM stage of tumor. The gene discussed is CD40LG; the disease is neoplasm.