KCNQ2 and Tinnitus: Taken together, our results suggest that experience-dependent bidirectional plasticity of KCNQ2/3 channel activity is associated with the vulnerability and resilience to noise-induced tinnitus: experience-dependent depression in KCNQ2/3 channel activity is important for vulnerability, while experience-dependent recovery in KCNQ2/3 channel activity is important for resilience to tinnitus.