However, there were no significant differences found in terms of age at diagnosis, gender, tumor depth, lymph node metastasis, vascular invasion, perineural invasion, pre-operative serum albumin level, the percentages of patients with diabetes mellitus, the percentages of patients receiving chemotherapy, the frequencies of cardiac disease comorbidity, the frequencies of renal disease comorbidity, or BMI. The gene discussed is ALB; the disease is heart disorder.