However, there were no significant differences found in terms of age at diagnosis, gender, lymph node metastasis, vascular invasion, perineural invasion, pre-operative serum CEA level, pre-operative serum albumin level, the percentages of patients with diabetes mellitus, the percentages of patients receiving chemotherapy, the frequencies of cardiac disease comorbidity, the frequencies of renal disease comorbidity, or BMI. The gene discussed is CEACAM5; the disease is metastatic malignant neoplasm in the lymph nodes.