Particularly, 17β-HSD1, 17β-HSD2, and 17β-HSD12, with ∼25–40% sequence homology, are involved in the control of the ratio of active to inactive estrogens and androgens, and they are known to play a role in prostate and breast cancer, letting us to hypothesize that DHRS7 function might affect tumor growth 17–19. Here, DHRS7 is linked to neoplasm.