Ten genes that showed significant differentially expressed between AD and CRM in the RNA-seq analysis (DDX60, IFH1, IFITM3, IGHMBP, MOV10, OAS1, PML, RNF213, TNFAIP6, TRIM5) were analyzed by real-time qRT-PCR in an independent patient cohort. This evidence concerns the gene PML and Alzheimer disease.