In COPD, FAM13A rs7671167 was the most significantly associated (P = 0.029; OR = 0.7; 95%CI: 0.5–0.97), whereas in combined COPD with LC+COPD, the FAM13A rs2869967 was the most relevant (P = 0.04; OR = 1.3; 95%CI: 1–1.7). The gene discussed is FAM13A; the disease is chronic obstructive pulmonary disease.