AKT1 and neoplasm: In the proliferation assay, OT-1 cells transduced with control retroviruses slowed proliferation on exposure to B16-OVA tumor cells, whereas OT-1 cells transduced with either wtAkt or myr-Akt displayed higher proliferation rates when cultured alone, and further increased the percentage of proliferative populations when co-cultured with B16-OVA (Fig. 2b).