Interestingly, we revealed significantly higher production of some pro-angiogenic factors by ADSCs: VEGF and HGF for patients with CAD and HGF and PlGF for patients with CAD+T2DM, whereas the angiogenic activity of all products secreted by ADSCs from patients with both CAD and CAD+T2DM was significantly decreased compared to the control group. Here, PGF is linked to coronary artery disorder.