In contrast, when investigating the DNA methylation status of ATAD2 (through 13 specific ATAD2 probes available in the k450 DNA methylation dataset from TCGA), we found the gene to be almost completely hypomethylated, suggesting that loss of DNA methylation is not a plausible mechanism providing elevated ATAD2 levels in endometrial cancer (Supplementary Figure S1B). Here, ATAD2 is linked to endometrial cancer.