At the transcriptional level, miR-7 expression has been shown to be promoted by epidermal growth factor receptor (EGFR) signaling in lung cancer via Rat sarcoma (Ras)/extracellular signal-regulated kinase (ERK)/v-Myc avian myelocytomatosis viral oncogene homolog (c-Myc) and phosphoinositide 3-kinase (PI3K)/v-Akt murine thymoma viral oncogene homolog (Akt) pathways. The gene discussed is MYC; the disease is lung cancer.