Most of the lung cancer tissues showed an inverse correlation of expression between miR-224 and CASP3, CASP7, with high expression of miR-224 and low expression of CASP7 (Figure 4a) and/or CASP3 (Figure 4b) respectively, and the expressions of miR-224 and CASP7 (Figure 4c) or CASP3 (Figure S4) were basically mutually exclusive. The gene discussed is CASP7; the disease is lung cancer.