Real-time RT-PCR revealed that expression levels of CEBPD (P<0.001) were most significantly upregulated in tumor samples featuring gains on 8q11.21 followed by KIAA0146 (P=0.023) (Figure-1D), thereby reinforcing the role of CEBPD as an amplification-driven gene in UBUC. This evidence concerns the gene SPIDR and neoplasm.