Stromal ALDH1 staining evaluated in primary tumors and/or lymph node metastasis indicated longer disease-free, metastasis-free and overall survival (Kaplan-Meier log rank analysis, p = 0.001, p = 0.005 and p = 0.004, respectively) (Figure 2). This evidence concerns the gene ALDH1A1 and metastatic malignant neoplasm in the lymph nodes.