Based on univariate analysis, high ROR2 expression (P < 0.001), high Wnt5a expression (P < 0.001), tumor TNM stage (P < 0.001), tumor status (T) (P = 0.040), lymph node metastasis (N) (P < 0.001) and high expression of both ROR2 and Wnt5a (P = 0.001) were associated with 5-year survival rate of NSCLC patients. The gene discussed is WNT5A; the disease is non-small cell lung carcinoma.