LPL and inflammatory bowel disease: While it is possible that effector T cells from the LPL of IBD patients could only have a defective response only to autologous Tregs, not revealed by the allogeneic Tregs used in our study, no such defect was revealed in published reports using auotologous Tregs and effector T cells from the blood[27] or MLN[10,11] of IBD patients relative to controls.