CD33 and acute myeloid leukemia: On the other hand, in experiments in which an E:T cell ratio of 3:1 was used, there was a statistically significant correlation between CD33 expression on AML blasts and AMG 330-induced cytotoxicity (at 250 pg/mL: r = 0.457 [0.165–0.676], P = 0.0027; at 500 pg/mL: r = -0.465 [0.174–0.681], P = 0.0022; Fig 3C).