A similar mechanism of action on MSK1 was seen in human keratinocytes and in dendritic cells by dimethyfumarate (DMF) as an anti-psoriatic agent [61] and a therapeutic agent for multiple sclerosis [62], respectively, as well as in mouse skin by docosahexaenoic acid (DHA) [63]. The gene discussed is RPS6KA5; the disease is multiple sclerosis.