For example, a case-control study among postmenopausal women enrolled in the Multiethnic Cohort Study (706 cases; 706 controls) found that women in the highest quartile of CRP were significantly more likely to develop breast cancer than women in the lowest quartile (OR: 1.41; 95% CI 1.01–1.96; Ptrend = .01) [4]. This evidence concerns the gene CRP and breast cancer.