AR and neoplasm: To prove the above in vitro data in vivo, we first generated the miRNA-145-expressing OSRC-2 cells (Figure 6A) and then orthotopically xenografted these OSRC-2 cells (OE AR+OE miR-145; OE AR+NC; Vec-AR+OE miR-145 and Vec-AR+NC) under the nude mice kidney capsules (1×106 cells) with IVIS Imaging system to monitor tumor progression.