The median concentration of serum cPL in dogs with SIRS was 158 μg/L (interquartile range: 52.5 μg/L – 571.5 μg/L; n = 53), which was significantly higher than in those without SIRS (75 μg/L; 50.3 μg/L – 131.8 μg/L; n = 32) (P = 0.018). Here, HEPH is linked to systemic inflammatory response syndrome.