The Residual Risk Reduction Initiative (R3I) has identified atherogenic dyslipidemia (imbalance between proatherogenic triglyceride-rich apolipoprotein B-containing lipoproteins and antiatherogenic apolipoprotein A-I-lipoproteins) as an important modifiable contributor to residual cardiovascular risk, and highlighted the need for education to improve awareness of this condition [45]. This evidence concerns the gene APOB and metabolic syndrome.