KCNN4 and myocardial infarction: Population analysis has identified several single-nucleotide polymorphisms (SNPs) in both coding and noncoding regions of the KCa2.3 and KCa3.1 genes.162 Currently, the only suggestion of genetic linkage to cardiovascular dysfunction is the finding that an intronic SNP in the KCa3.1 gene was significantly less prevalent in a cohort of 313 Japanese patients who had myocardial infarctions than in a control group.163