In patients with the X-linked erythrocyte enzyme disorder glucose-6-phosphate dehydrogenase deficiency (G6PDd), primaquine causes dose-dependent acute haemolytic anaemia (AHA) that is greater in the more severe deficient G6PD variants; AHA can be potentially life threatening but primaquine-related deaths are very rare [9–15]. Here, G6PD is linked to autoimmune hemolytic anemia.