DGKζ promotes mTORC1 activation in response to serum in renal carcinoma cells22 and in C2C12 myoblasts.23 We tested the effect of DGKζ silencing by determining phosphorylation of the mTOR substrate p70S6K at various times after serum addition to SW480 cells. The gene discussed is DGKZ; the disease is renal carcinoma.