In our efforts to evaluate the function of the IL-8 receptor CXCR2 in ALL cells, we made use of SB225002 (N-(2-hydroxy-4-nitrophenyl)-N’-(2-bromophenyl)urea), a drug initially described as a CXCR2 antagonist [2]. The gene discussed is CXCR2; the disease is acute lymphoblastic leukemia.