ANXA5 and acute lymphoblastic leukemia: To determine if the deleterious effects of SB225002 in ALL were caused by the induction of apoptosis, we performed Annexin-V/Propidium Iodide (PI) analysis in B-ALL (REH and RS4;11) and T-ALL (Jurkat and TALL-1) cells treated with SB225002 [10 μM] for 24 h.