As, H2170 cells have upregulated and constitutively activated p-EGFR [17], this suggests that EGFR and Wnt pathways may converge at β-catenin, [51] and thus, cooperatively enhance tumorigenesis in H2170-ER and H2170-SR cells, which has also been suggested by other investigators in other cancers [18,52–55]. This evidence concerns the gene EGFR and cancer.