LGALS3 and thyroid cancer: In another study, Weber analyzed the use of TPO and galectine-3 separately for the diagnosis and prognosis of thyroid cancer — also combining both markers — and obtained with TPO staining a sensitivity of 39 % for any cancer, of 50 % for PTC, and of 11 % for FTC, which increased with galectine-3 immunostaining to 82 %, 96 % and 44 %, respectively [18].