PAX8 and thyroid gland papillary carcinoma: Rosen [5] compared gene expression in benign thyroid lesions versus papillary carcinoma, and described a set of 6 genes that predicted pathological diagnosis with 75 % sensitivity and 100 % specificity; Kroll [6] described fusion protein PAX8/PPAR-γ as a marker to distinguish benign from malignant follicular lesions.