Other rarer causes of TNDM include heterozygous mutations in genes encoding sub-units of ATP-sensitive potassium channel: potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11) (Flanagan et al., 2007), ATP-binding cassette, sub-family C, member 8 (ABCC8) (Patch et al., 2007) and bi-allelic mutations in zinc finger protein 57 (ZFP57) (Mackay et al., 2008). Here, ABCC8 is linked to transient neonatal diabetes mellitus.